There’s a lot of talk about the medical value of Cannabis.What are endocannabinoids and how marijuana impacts our organism? First of all let’s start by saying that our body makes its own cannabinoids.Our bodies produce some acids (anandamide and 2-arachidonoylglycerol) and we also possess some special endocannabinoid ( they are called CB-1 and CB-2 ) receptors that interact with our endogenous cannabinoids. The endocannabinoid system (ECS) is classified as a neurotransmitter system, and has ancient origins.
The endocannabinoids are mainly responsible for getting people high when it interacts with THC. The CB-1 receptor is found in our brains and neural system and is responsible for motor control and behavioral responses while the CB-2 is located throughout our body, and concentrated in several organs and our immune system. It affects our digestion and how our immune system responds to illnesses and pain.We are able to feel the effects of cannabis because our bodies already have similar compounds aka endogenous cannabinoids or endocannabinoids. But as we said, the ECS is not just there to make you enjoy smoking weed, it’s a vital part of the body. We may use to imagine only bongs when we hear about Cannabis, but science proves that there is a lot more than that.
The most important cannabinoids are THC and CBD, which are the ones that interact most uniquely with the ECS. When THC interacts with CB-1 generates the “high effect” while CBD that interacts with CB-2 creates no psychoactive results.
The human experience has studied the cannabinoids effects. Although Cannabis is currently recognized by the U.S. Drug Enforcement Agency’s Comprehensive Drug Abuse Prevention and Control Act of 1970 as a Schedule I controlled substance many medical clinics offer legal marijuana for its many positive effects on diseases and Cannabis use for medical purposes is legal in most of the States of America. It has been proven that migraine, fibromyalgia, irritable bowel syndrome, and related conditions represent clinical eCB (endocannibinoids) deficiency syndromes (CEDS). In human studies, eCB system deficiencies have been implicated in schizophrenia, multiple sclerosis (MS), Huntington’s disease, Parkinson’s disease, anorexia, and chronic motion sickness. Since all of these diseases and disorders stem from a lack of endocannabinoids, it stands to reason (though hasn’t been scientifically proven) that ingesting cannabinoids could help alleviate symptoms and possibly cure problems.
CBD is considered a great pain aid (both chronic and neuropathic) and it seems to have a high value for therapies including the use as antipsychotic, anti-inflammatory, and neuroprotective. Preliminary clinical trials suggest that also may have a therapeutic effect against epilepsy, insomnia, and social anxiety disorder.